Hi! 👋
My current research centers around developing computational methods to
uncover elusive genetic underpinnings
of human health conditions such as cancer,
Mendelian disorders, and
unexpected treatment responders.
Pinpointing disease-relevant genetic variants that defy detection
can shine a light on the limits of our biological and medical knowledge and
requires the development of computationally tractable and interpretable models that
integrate high-throughput functionality data,
population-level 'omics data, and clinical health data.
I chair the Tool Building Coalition working group in the
Undiagnosed Diseases Network, teach
about genome sequencing analysis
for rare disease diagnosis,
and mentor and advise undergraduate, Master's, and PhD students on their research projects.
My mental and creative energy is also drawn in many other (rewarding, demanding, typically unacknowledged) directions: I coordinate the Tykes league through
Somerville Youth Soccer, am a trustee for our
self-managed 6-unit condo (and oversee our budget, legal paperwork, and large construction projects), and am the
parent–teacher liaison and volunteer coordinator for my eldest kiddo's (public school) classroom.
I love DIY house projects, camping and backpacking with my kids, and seeing live music.